This subsection of the Names and taxonomy section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. have the same checksum value, the likelihood that this would happen
This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (UniRef).
This potassium channel is controlled by G proteins. It plays a role in granule cell differentiation, possibly via membrane hyperpolarization. It is updated at every UniProt release.The Gene Ontology (GO) project provides a set of hierarchical controlled vocabulary split into 3 categories:
Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.Please consider upgrading Potassium channel, inwardly rectifying subfamily J member 4The Val/Gly/Ala/Pro stretch may have a functional role in the conductance or permeation properties. of multiple genes (paralogs). Like voltage-gated potassium channels, they are tetramers and contain a P region that forms part of the ion selectivity filter, but they contain only two transmembrane segments, M1 and M2. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.
Inferred from Physical Interaction
They have four transmembrane segments and resemble two inward rectifier subunits fused together. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.Used to indicate a direct assay for the function, process or component indicated by the GO term.
They are activated by phosphatidylinositol 4,5-bisphosphate (PIP 2).The malfunction of the channels has been implicated in several diseases. By providing access to the largest selection of ion channel reagents, an expert team and state-of-the-art electrophysiology equipment, we accelerate ion channel drug discovery and simplify off-target safety testing.Our cell biology expertise takes the stress out of cell line generation.This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.
It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. https://psychology.wikia.org/wiki/Inward-rectifier_potassium_ion_channel TAX1BP3 competes with LIN7 family members for KCNJ4 binding.The Biological General Repository for Interaction Datasets (BioGRID)The Eukaryotic Linear Motif resource for Functional Sites in ProteinsRNAct, Protein-RNA interaction predictions for model organisms.SWISS-MODEL Repository - a database of annotated 3D protein structure modelsRelative evolutionary importance of amino acids within a protein sequenceevolutionary genealogy of genes: Non-supervised Orthologous GroupsThe HOGENOM Database of Homologous Genes from Fully Sequenced OrganismsIdentification of Orthologs from Complete Genome DataDatabase for complete collections of gene phylogeniesGene3D Structural and Functional Annotation of Protein FamiliesIntegrated resource of protein families, domains and functional sitesProtein Motif fingerprint database; a protein domain databaseSuperfamily database of structural and functional annotationDNA Data Bank of Japan; a nucleotide sequence databaseProtein sequence database of the Protein Information ResourceChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing dataThe Gene Wiki collection of pages on human genes and proteinsDatabase of phenotypes from RNA interference screens in Drosophila and Homo sapiensThe Stanford Online Universal Resource for Clones and ESTsProtoNet; Automatic hierarchical classification of proteinsMobiDB: a database of protein disorder and mobility annotationsYou are using a version of browser that may not display all the features of this website. Cyclic redundancy and other checksums
This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.
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